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Remember Viagra will only get you hard when it’s combined with sexual stimulation. The highest dose is reserved for particular cases where the generic Viagra dosage of 50mg has already been found to be lacking. QUALITY AND SAFETY GUARANTEEDAll prescriptions are sourced only by US FDA, HPB, and UK or equivalent approved PHARMACIES to ensure the highest quality and safety of the products. The generic version, sildenafil, is currently available in the U.S. and at accredited international online pharmacies. Men can save up to 99% off Viagra 100 mg by comparing Viagra (sildenafil) prices at Canadian and international online pharmacies with discount prices available at neighborhood U.S. pharmacies below.

This helps to ensure tablets are split evenly and minimises wastage by reducing any residue that can fall off a tablet when split incorrectly. You will not be suitable for Viagra and other ED medications if you are taking nicorandil or nitrates, such as GTN spray or isosorbide mononitrate tablets to treat angina. As this is a prescription-only medication, even if you are using an online service, you will need a prescription from a clinician before you can buy the treatment. You should not combine Viagra with other ED medicines including Spedra which can work within 15 minutes.

To get the maximum benefit from your medication, it is advisable not to drink excessive amounts of alcohol before taking this medication. A double-blind, placebo-controlled exercise stress trial evaluated 144 patients with erectile dysfunction and chronic stable angina who regularly received anti-anginal medicinal products (except nitrates). The results demonstrated no clinically relevant differences between sildenafil and placebo in time to limiting angina. Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum, where PDE5 is responsible for degradation of cGMP. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum but potently enhances the relaxant effect of NO on this tissue. When the NO/cGMP pathway is activated, as occurs with sexual stimulation, inhibition of PDE5 by sildenafil results in increased corpus cavernosum levels of cGMP.

Yes, age is something doctors keep in mind when deciding on the appropriate sildenafil dosage. Older people are generally prescribed Viagra at a lower dose because of their reduced kidney and liver function. As a result, drug metabolism slows down with age